Losectil Capsule 20mg
10 capsules
Losectil
Omeprazole Capsule Powder for Oral Super
DESCRIPTION
Losect capsule contains entre cosed peters of Oneprane Losec power br sapersion is preparation of Oneprazole Losect 4 V vection is a combination pack coning of a vial containing lyophilized powder of Omeprazole Sodium and a separate ampoule of racing on Oneprale is a specific rhblor of the gastric proton pump 0CxATPase the parietal out where produc dose dependent inhibition of and secretion by binding to the intyme and afectly dum gastric acid secretion This affect leads to ton of both basal and muted and sector pective of the simu Lesect powder for oral suspension is formulated as an inndelease one for oral administration. Ater oral administration, the orsel of the artsecretory sect occurs with wh the maximum effect occing within 30 minutes and hibition of section as up to 24 hours When the drug is dacontinued, secretory activity retums gradually, over 3 to 5 days
INDICATIONS
Treatment of oesophageal refus disease
2. Treatment of duodenal and benign gastric ulcers including those complicating NSAD 3. Relet of reflux the symptoms is g heartburn) and/or ulcerka symptoms gepigastric paint
associated with acid related dyspepsia 4 Treatment and prophylaxis of NSAID-associated benign gastric ulcers, duodenal ulcers, and
gastroduodenal ertion in-patients with a previous history of gastroduodenal sons that
require continued NSAID treatment 5. Relet of associated dyspeptic symptoms
Helicobacter pylor eradication: Omeprazole should be used in combination with andbotics for eradication of Helicobacter pylon in peptic ulcer disease
7 Prophylaxis of acid aspiration Zollinger-Ellison syndrome
DOSAGE AND ADMINISTRATION
Benign gastric ulcers
20 mg once daily for 8 weeks, in severe i recurent cases increase to 40 mg daily 20 mg once daily for 4 weeks in dutinal uker in severe or recurent cases create to 40 mg daly 20 mg once daily.
Duodenal ulcers
Maintenance for recurrent duodenal ulcer
Prevention of relapee in duodenal ulcer
10 mg daily increasing to 20 mg once daly symptoms retum
20 mg once daily for 4 weeks, followed by a
further 4 weeks if not tuly healed
NSAID-associated peptic ulcer
and
gastroduodenal erosions Prophylaxis in patients with a history of NSAID associated gastroduodenal lesions who require connued NSAID treatment
20 mg once daily
Zollinger-Ellison syndrome
Initially 60 mg once daily, usual range 20 120 mg daily (above 80 mg in 2 divided doses) orally or ravenously
Gastric acid reduction during anaesthesia iprophylaxis aspiration)
general of acid
40 mg on the preceding evening then 40
ing 2-6 hours before surgery
Gastro oesophageal reflux disease
20 mg once daily for 4 weeks, followed by a further 4-8 weeks not fully healed
Gastro oesophageal reflux disease refractory to other treatment
disease
Bong-term
Acid reflux management)
40 mg once daily has been given for 8 weeks may be continued at 20 mg once daly
10 mg daly increasing to 20 mg once daly symptoms retum
10-20 mg once daily for 2-4 weeks
according to response
20 mg twice daily plus amoxicillin 500 mg four times daily plus metronidazole 400 mg thrice daily for 2 weeks
Acid-related dyspepsis
Eradication of Helicobacter pylon
Duodenal ulcer, gastric ulcer or reflux oesophagitis where oral medication is
inappropriate
Losect 40 NV injection once daily is recommended
Paediatric Patients
For the treatment of GERD and maintenance of healing of erosive esophagitis, the recommended daily dose for paediatric patients 1 to 16 years of age is as follows
Omeprazole Daily Dose 5mg
Patient Weight 5 to <10 kg
10 to 20 kg 220 kg
10 mg
20 mg
On a per kg basis, the doses of omeprazole required to heal erosive esophagitis in
HETHER OF AD
wod of 25-30 hoty has 1 hours
Mouton with N Dece
CONTRAINDICATIONS Ompra
contraindicated in parts with a UE IN PREGNANCY AND LACTATION Pregnancy ser mothers Omprarely
LICE AFFECTS
On generally we at Ne healere, dantes colon and Re Pape but are rare Skarshe have occurred a few plate These avere have y
DRUG INTERACTIONS Omeprazole can delay the men of darepe, phenytoin and wartan Moning of patients
wowing warfarin or phenytoin is recommended and a reduction of warfarin or phenytoin dose may be
necessary, when Omeprazole is added to treatment
PRECAUTIONS
Before treatment the presence of gastric malignancy should be excluded.
PHARMACEUTICAL PRECAUTION
Sore between 15-30° C, protected from light Powder for oral suspension Sove at or below 25 C temperature, Keep away from light & wet place
Capsule
Vinjection
PACKAGING
Capsule: Losectil 10 capsule
Box containing & strips of 10 capsules each. Each capsule contains Omeprazole USP 10 mg as enteric coated pellets
Losectil 20 capsule
Losectil 40 capsule
Box containing 10/12 strips of 10 capsules each. Each capsule contains Omeprazole USP 20 mg as enteric coated pellets.
Bex containing 10 strips of 6 capsules each. Each capsule contains
Omeprazole USP 40 mg as enteric coated pellets.
Powder for Oral
Each box contains 50 sachets. Each sachet contains Omeprazole USP 20 mg as immediate release formulation
Losectil 20
Losectil 40
Each box contains 30 sachets. Each sachet contains Omeprazole USP 40 mg as immediate release formulation
IV Injection: Losectil 40 IV injection
Box containing one vial of Sterile Omeprazole Sodium (as Lyophilized powder) equivalent to Omeprazole 40 mg and one ampoule of 10 mL Chloride BP 0.9% Injection
Do not store above 25 °C. Keep away from light & wet place. Keep out of
reach of children
Manufactured by
ESKAYEF PHARMACEUTICALS LTD.
RUPGANJ, NARAYANGANJ, BANGLADESH.